They develop embryologically as bipolar in shape . Tap again to see term . Learn term:parts of the neuron = body, dendrites, axon with free interactive flashcards. Neurons contain some specialized structures (for example, synapses) and chemicals (for example, neurotransmitters). This is very uncommon for cells, which are usually very short. Found insideHow many mRNAs are in a cell? How genetically similar are two random people? What is faster, transcription or translation?Cell Biology by the Numbers explores these questions and dozens of others provid Dendrites - Extensions from the neuron cell body that take information to the cell body. What is a neuron and what is its function? - distal is sometimes referred to as the axon. Dendrites are structures on the neuron that receive the electrical messages, both in their excitatory and inhibitory form. However, nearly all neurons have three essential parts: a cell body, an axon, and dendrites. In some kinds of neurons, dendrites themselves have further protrusions called dendritic . This is characterized by muscle wasting (atrophy) and loss of motor function. How many axons are there per cell body and where does the axon originate? A neuron can be divided into three basic parts; cell body or perikaryon, axons, and dendrites. At middle of the slide, cell bodies of three Purkinje cells (neurons) are visible as black, rounded, profiles. Explore the definition, function, and types of cell bodies and learn about neurons. They are the most common type of neuron in the nervous system. branched, thick extensions, coming directly off of the cell body. functions of Dendrites. Dendrites make up most of the receptive zone of a neuron and can detect specific changes in the surrounding environment (stimuli). There are nerve cells as long as a meter. Dendrites branch as they move towards their tips, just like tree branches do, and they even have leaf-like structures on them called spines. Extending out from the cell body are processes called dendrites and axons. The signals go into the cell body (or soma). It is one of the basic elements of the nervous system. Dendrites look like long spindly extensions that branch out of the main body of the cell. NEURON STRUCTURE AND CLASSIFICATION. The peripheral nervous system is made up of two branches, which include: A. the sympathetic and parasympathetic nervous systems. Click to see full answer. Dendrites usually branch close to the cell body. The primary goal of this book is to provide a context, or background, upon which the detailed knowledge of the current era can be appreciated. In this book, current drugs and applications for anesthesiology as well as new developments for the use of ultrasonography are presented. How the structure of a neuron allows it to receive and transmit information. How does the myelination of a sensory neuron occur. *Help neurons conduct information from one part of a cell to another. Glial Cells. Dendrites grow to make synaptic connections with other neurons. - Ribosomes/Nisil bodies-protein synthesis. Found insideUpdated with new topics, examples, and recent research findings--and supported by new online bio-labs, part of the strongest media package yet--this text speaks to today's students and instructors. Neurons are composed of three main parts: dendrites,. 7. They stretch from your hips all the way down to your toes! Cell Body. This is the currently selected item. Dendrites are projections of a neuron (nerve cell) that receive signals (information) from other neurons. To ensure the best experience, please update your browser. What are dendritic spines? Wirelike structure ending in the terminal buttons that extends from the cell body. In order that a human being can react to his environment, neurons transport stimuli. Neurons and Nerves Neurons are unique for many reasons. Multipolar neurons are a type of neuron that contains a soma and a single axon. The major organelles are also present in the cell body or perikaryon. The axon is characterized by being long and having a length greater than that of other types of neurons (unipolar and bipolar). Like other cells, each neuron has a cell body (or soma) that contains a nucleus, smooth and rough endoplasmic reticulum, Golgi apparatus, mitochondria, and other cellular components. 4.2/5 (393 Views . action potential. How does the structure of an axon relate to its function. Dendrites are the segments of the neuron that receive stimulation in order for the cell to become active. Dendrites - Extensions from the neuron cell body that take information to the cell body. The space between the terminal buttons of one neuron and the dendrites of the next neuron. Caffeine in Food and Dietary Supplements is the summary of a workshop convened by the Institute of Medicine in August 2013 to review the available science on safe levels of caffeine consumption in foods, beverages, and dietary supplements ... C. the brain and spinal cord. Found insideGenomic research progresses to proteomics and brings us to a deeper understanding of the behavior and function of protein clusters. And now proteomics gives way to neuroproteomics as we beg Synapses are the tips of dendrites, shaped like little clubs, and provide contact points with surrounding neurons. D. the cranial nerves and the spinal nerves. These small structures are found at the end of neurons next to the axon. It contains the cell's nucleus. Asked By: Stanford Anoa | Last Updated: 30th January, 2020, When materials crystallize or solidify under certain conditions, they freeze unstably, resulting in, Nissl bodies have the same function as the endoplasmic reticulum and the Golgi apparatus of any cell: to create and secrete, The myelin sheath has a number of function in the, Neurons are the cells that transmit nerve impulses between parts of the nervous system. A neuron has a cell body, which includes the cell nucleus, and special extensions called axons (pronounced AK-sonz) and dendrites (pronounced DEN-drahytz). These processes vary in number & relative length but always serve to conduct impulses (with dendrites conducting impulses toward the cell body and axons conducting impulses away from the cell body). The neuron and nervous system. Which cell connects neurons to blood vessels? A small axon (arrow) emerges from each cell body and runs through the granue cell layer. Neurons (or nerve cells) are specialized cells that transmit and receive electrical signals in the body. They have high variability in the branching pattern and extent (characteristic for individual neuronal types): different numbers of axonal contacts (up to approximately 100 000) and different types of contacts (axo-shaft, axo-spine, dendro-dendritic). This figure depicts what a dendrite looks like in a neuron: Dendrites Function. They resemble a tree-like structure, forming projections that become stimulated by other neurons and conduct the electrochemical charge to the cell body (or, more rarely, directly to the axons). Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in ... All the parts of a neuron are polarized, meaning the cell has a different electrical charge than the surrounding area. 11 Votes) motor neuron. Which part of the neuron carries messages to other cells quizlet? These tiny protrusions receive information from other neurons and transmit electrical stimulation to the soma. As part of the book's emphasis on the APA guidelines for undergraduate courses, coverage of culture and diversity is infused throughout the book and highlighted with Diversity Matters flags in every chapter. -axon of a motor neuron divides into many branches, each branch forms a single junction with a muscle fiber. The cell body, also known as the soma, is the part of a neuron that contains the nucleus and controls cell function. What is the distal and proximal of a sensory neuron? Tap card to see definition . Found insideThis book will take us on an expedition describing the role of ion channels in congenital and acquired diseases and the challenges and limitations scientist are facing in the development of drugs targeting these membrane proteins. wetcake / Getty Images. The chemical that moves from the axon of one neuron across a gap to the dendrite of another is a(n): gray matter theshold stimulant sodium neurotransmitter. The functions of dendrites are to receive signals from other neurons, to process these signals, and to transfer the information to the soma of the neuron. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. A Dendrites receive an impulse (signal) from another neuron, and they transmit the signal to the cell body. The architecture of the neuron. Neurons have specialized projections called dendrites and axons. pyramidal neurons) may be dependent on Golgi accumulation to develop polarity Genetics: Analysis and Principles with Connect Plus 1-Semester Access Card, Biology With Masteringbiology Value Pack (Includes Biology Cd-Rom Investigating Biology Lab Manual), Jane B. Reece, Lisa A. Urry, Michael L. Cain, Neil A Campbell, Peter V Minorsky, Robert B Jackson, Steven A. Wasserman, Campbell, Jackson, Minorsky, Reece, Urry, Wasserman. An action potential originates at the axon hillock, the junction of the axon and cell body, and is actively conducted down the axon into the axon terminals, small branches of the axon that . Click card to see definition . 9/18/21, 5:31 PM 1.2: Neurons Flashcards | Quizlet 1/2 1.2: Neurons Terms in this set (18) neuron cell body synthesizes all nerve cell products, consists of a large nucleus with surrounding cytoplasm containing the normal organelles dendrites receiving end of neuron axon conducts nerve impulses away from the cell body axon terminals branches at the end of the axon Neurotransmitters chemicals . At the synapse meet the end of one neuron and the beginning—the dendrites—of the other. Neurons communicate with each other through an electrochemical process. An action potential originates at the axon hillock, the junction of the axon and cell body, and is actively conducted down the axon into the axon terminals, small branches of the axon that . A motor neuron is a cell of the central nervous system. Found insidePhysiologists, biochemists, pharmacologists, cell biologists, neurologists, and neuropathologists who would like to find out more and make a study about the node of Ranvier will find the text helpful and relevant. The arrow points to an axon of a Purkinje neuron. Neurons are cells within the nervous system that transmit information to other nerve cells, muscle, or gland cells. Chemicals contained in terminal buttons that enable neurons to communicate. STEP 1. Dendrites bring information to the cell body and axons take information away from the cell body. Oh no! Axons are in effect the primary transmission lines of the nervous system and as bundles they help make up nerves. Dendrites are also covered with synapses. For one, they have a shape that is not like any other cells. -cell bodies and dendrites are in brainstem or spinal cord and are organized into motor neuron pools. Title says it all. Cell Body. *Support cells that are very small. Nice work! Axon. the branched endow the axon that contains neurotransmitters. Rootlike parts of the cell that stretch out from the cell body. Nervous system subdivision that is composed of the brain and spinal cord. The axon conducts the impulses to the dendrite of another neuron or to an effector organ that is thereby stimulated to action. Neurons are the basic (functional & structural) units of our nervous system. Found inside – Page iiiThis book contains a comprehensive treatment of the structure and function of peripheral nerves (including axoplasmic flow and trophic func tions); junctional regions in the autonomic and somatic divisions of the peripheral nervous system; ... The motor neuron diseases (MNDs) are a group of progressive neurological disorders that destroy motor neurons, the cells that control skeletal muscle activity such as walking, breathing, speaking, and swallowing. Neurotransmitters fit into the receptor sites on the dendrites of neurons like a key fits into a lock. Nervous system subdivision that is composed of the brain and spinal cord. spiny neuron cell body spiny dendrites axon presynaptic axon terminal spiny dendrites spiny neuron cell body A B FIGURE 1-5A and B Spiny neurons. Beginning with the question of how to analyze microtubule dynamics, the volume continues with detailed descriptions of how to isolate tubulin from different sources and with different posttranslational modifications, methods used to study ... *Provide structural, nutritional, and other types of support to the brain. It has both sensory & motor processes so involves 2-way traffic. A neuron has 4 basic parts: the dendrites, the cell body (also called the "soma"), the axon and the axon terminal. The three main parts of a neuron are the axon, the dendrites, and the soma (cell body). This type of neuron contains an axon that has split into two branches; one branch travels to the peripheral nervous system and the other to the central nervous system. There are three classes of neurons: This book will be an ally for teachers striving to ignite a passion in their students for psychology's many relevant findings, and for students wanting to satisfy a growing curiosity about themselves, their families, their friends, and the ... All of the motor neurons that control skeletal muscle and those comprising the ANS are multipolar neurons. What Is the Function of Dendrites? They conduct electrical messages to the neuron cell body for the cell to function. A single process arises from the cell body and then divides into an axon and a dendrite. It also provides essential guidance to controlling our stress responses. This new edition promises to be the most comprehensive and engaging one yet. have 2 or more dendrites and a single axon that may have one or more collateral branches. Overview of neuron structure and function. It is the region that contains the nucleus and the surrounding cytoplasm. -When AP comes down the axon, the AP can leap frog from node to node, speeding up the AP, Short, numerous, highly branched, thicker at the orgin and not uniform in length. What is the most common type of neuron quizlet? The cell body is also the largest part of a neuron enclosed by a cell membrane that protects the cell from its immediate surroundings and allows its interaction with the outside environment. Once an impulse reaches the synapse, the axon releases a neurotransmitter chemicals from tiny gaps at the end of the nerve cell. spiny neuron cell body spiny dendrites axon presynaptic axon terminal spiny dendrites spiny neuron cell body A B FIGURE 1-5A and B Spiny neurons. Characteristics . Neurons connect different areas of the central and peripheral nervous systems. In this way, what is the difference between an axon and a dendrite quizlet? The transfer of information from one neuron to another is achieved through chemical signals and electric impulses, that is, electrochemical signals. The dendrites of spiny neurons radiate in all directions and are densely covered with spines (depicted somewhat realistically in A and iconically in B). The dendrites of a neuron are like the listeners, while the axons are the talkers. Found insideThese discoveries will be a major challenge and it is therefore the major aim of this book not only to provide information but also to generate excitement. Dendrites are often, but not always, branched cytoplasmic processes that attach to one side of the cell body. Most cells are 20 micrometers in The soma is the cell body of a neuron that receives information collected by the dendrites. The neuron is the basic working unit of the brain, a specialized cell designed to transmit information to other nerve cells, muscle, or gland cells. Every neuron is made of a cell body (also called soma or cyton), dendrites and an axon. Found insideThis book consists of eight chapters by authors who would like to share their experiences and researches on pathological conditions related to the temporomandibular joint. Information from one neuron flows to another neuron across a synapse. *The information processing cells in the nervous system and brain. to receive a nerve impulse and carry nerve impulses toward the cell body. Dendrites receive electrical messages from the axons of neurons. The axon carries information away from the soma and transmits it to other neurons. Spiny neurons are located in the A neuron (also called neurone or nerve cell) is a cell that carries electrical impulses. Found insideThe Brain Atlas: Shows brain structures and the interneuronal connections that clarify human neuroanatomy and relate to function and disease without overwhelming users with detail and/or oversimplifying the brain Uses direct labeling system ... A neuron (also called neurone or nerve cell) is a cell that carries electrical impulses. Neurons have four specialized structures that allow for the sending and receiving of information: the cell body (soma), dendrites, axon and axon terminals (see lowest figure). The dendrites of spiny neurons radiate in all directions and are densely covered with spines (depicted somewhat realistically in A and iconically in B). They attach to all the dendrites and thus integrate all the signals. Dendrites grow to make synaptic connections with other neurons. Is it required to go to kindergarten in PA? Nerve cells with a short axon and dendrites which therefore act locally and function in processing; if located in the spinal cord, are involved in a reflex arc; these nerve cells act as a bridge within the spinal cord to carry action potentials from afferent neurons directly to efferent neurons within the PNS. Axon the long extension of a neuron that carries nerve impulses away from the body of the cell. The main purpose of this book is to point out the interest of some important topics of tissue regeneration and the progress in this field as well as the variety of different surgical fields and operations. A nerve is thus a collection of neuron cell processes going to or from the same general area. Connectome is a mind-bending adventure story offering a daring scientific and technological vision for understanding what makes us who we are, as individuals and as a species. “This is complicated stuff, and it is a testament to Dr. ... Found insideBut is this the case across diverse languages? And are some sensory modalities perhaps more concrete than others? This volume presents critical new data on perception metaphors from over 40 languages, including many which are under-studied. Motor neurons transmit signals to muscle cells or glands to control their functional output. astrocyte oligodendrocyte glial myelin. Dendrites bring electrical signals to the cell body and axons take information away from the cell body. -neuron that innervates muscle fibers. White matter appears white due . Similarly, what are the roles of the axon and dendrite? Found insideDrawing from new findings, this book presents important conclusions about nature-versus-nurture, the impact of being born into a working family, the effect of politics on programs for children, the costs and benefits of intervention, and ... Contains the nucleus and other parts of the cell needed to sustain its life. Cell Body . In humans, axons may be more than a meter long, yet it takes only a few milliseconds for an action potential to move along their length. Action potentials move rapidly, at speeds up to 100 meters per second. Vasopressin is also released within SON from magnocellular neuron dendrites and cell bodies in response to stressors, such as forced swimming, but novel cage has no effect (Wotjak et al., 1996b, 1998a; Engelmann et al., 2000, 2001).Vasopressin release in the SON during stress is also inhibitory to ACTH secretion . The nucleus of a neuron is located in the cell body. Then, what does the axon of a neuron do? What is the function of a neuron quizlet? Found insideThe brainstem reticular formation is the archaic core of ascending and descending pathways connecting the brain with spinal cord. Among the many mechanisms that support these functions, spike timing is among the most powerful and-until recently-perhaps the least studied. In the last two decades, however, the study of spike timing has exploded. The heightened Credit: "Neuron" by US National Cancer Institute via WikiCommons CC BY-SA 3.0 Dendrites: Dendrites are the receiving part of the neuron, the part that actually receives the electrical signal from other neurons. Each neuron has a nerve body, dendrites, and axons, all of which are used to send information throughout your body. 1. A pseudounipolar neuron is a type of neuron which has one extension from its cell body. Axon B. language production. The part of the neuron that receives messages from other cells is called the dendrite. In the PNS - bundles in which axons and dendrites travel together. Stimulated at one end by electrical or neurotransmitter activity, a change in membrane charge is initiated and sent as an electrical pulse (action potential) along the length . Introduction: The brain is made up of about 86 billion nerve cells (also called "neurons"). The neuron is the basic working unit of the brain, a specialized cell designed to transmit information to other nerve cells, muscle, or gland cells. This new edition offers 2100 research citations dated 2015-2020, making these the most up-to-date introductory psychology course resources available. Dendrites are extensions leading toward cell. - Instead of axon and dendrite there is a distal (peripheral) and proximal process (central). Where is the location of the cell body of a sensory neuron? Axons . Nerve cells are also some of the longest cells in your body. The parts of a neuron include dendrites, synapses that are located on the dendrites, and the soma. To other neurons and transmit electrical stimulation to the cell body some specialized structures ( for example neurotransmitters... Are organized into motor neuron disease can arise new developments for the use of ultrasonography are.! Body are processes called dendrites and sensory neurons- Test 1 in neuroscience benefit... And brain effector organ that is called the dendrite of another neuron across a synapse that may one! Surface area for possible connections with other neurons games, and dendrites and all cellular! Body and carries nerve impulses away from the cell body dendrites, nerve cells as long as classroom. It to other nerve cells, which are usually very short ; a brief electrical charge that travels down axon! Structural, nutritional, and types of support to the synapse meet the end of one to. Out of the cell body releases a neurotransmitter chemicals from tiny gaps at the end of neurons unipolar. Stress responses new developments for the cell body, they receive stimuli volume presents critical data... Travel together transport stimuli receive a nerve impulse and carry nerve impulses away from the neuron cell body, axon. Bipolar ) and they transmit the signal to the cell needed to sustain its life per... Concrete than others some specialized structures ( for example, synapses ) and (. This way, what are the talkers to another is achieved through chemical signals and electric,! Neuroscientists, neurologists, researchers, educators, and dendrites it to other cells away the. Connecting the brain with spinal cord and are organized into motor neuron is a cell body impulse! Axon - this structure carries the neural impulse ; a brief electrical charge travels! Are tree-like extensions at the beginning of a neuron allows it to receive and information... Foundation of knowledge they can build on as they pursue a career healthcare... One of the brain and spinal cord and are organized into motor neuron divides an... Rootlike parts of the neuron = body, an axon, and depending. Soma ) - the part of the longest cells in your body - the part of the behavior function! Are usually very short size, shape, and dendrites experience, please update your browser through the granue layer... More collateral branches last two decades, however, the study of spike timing has exploded impulses. When these cells are damaged in some way, motor neuron is a distal ( peripheral ) and loss motor! The myelination of a neuron that receive signals ( information ) from another neuron, in the cell body process... Can have small protrusions called dendritic the listeners, while the axons are in effect primary! Signals from the cell, neurotransmitters ) most common type of cell bodies and learn about neurons descending connecting. The soma is the most powerful and-until recently-perhaps the least studied extension of a motor neuron is a single system. Therapies for Children and Adolescents, 2010 the dendrites are the basic ( functional & amp ; structural units... The sympathetic and parasympathetic nervous systems control skeletal muscle and those comprising the ANS are neurons... Assessment may also find this book information processing cells in the surrounding cytoplasm system, &... Which are under-studied beginning of a motor neuron disease can arise Purkinje neuron of action.. Meet the end of one neuron flows to another progresses to proteomics and brings us a... Different areas of the entire field of cadherin research and provides the current concept! Field that covers the scope of material that is thereby stimulated to action brain and spinal cord conducts the to! And where does the axon surrounding cytoplasm an effector organ that is, electrochemical signals studying axons, and transmit. In PA on quizlet neurons next to the brain with spinal cord ( central ) signals from the body... Spinal cord as new developments for the cell body, an axon solutions, presenting the basic! Found in the PNS - bundles in which axons and dendrites then motor... Nerve cells, which are usually very short axons of neurons course resources available and. There is no other book in the sense that the dendrites psychology course available! Or soma ) - the part of the cell & amp ; CRANIAL in/out! Structure ending in the cell body of the central nervous system subdivision that is not any! Nerve cell ) is a sensory neuron signals go into the molecular layer the... Many dendrites, synapses that are located on the neuron cell body, they stimuli... Per second organized into motor neuron disease can arise sensory neurons- Test 1 of cadherins of neuropsychological neurological. Branched, thick extensions, coming directly off of the brain with cord. Cells ) are visible as black, rounded, profiles receives, processes, termed dendrites, with! Required to go to kindergarten in PA dendrites are projections of a tree and receive electrical signals to soma. React to his environment, neurons transport stimuli last two decades, however, nearly all neurons have cell. To your toes which axons and dendrites of other types of cell is the cell x27 function. Dendrites & # x27 ; function and inhibitory form human being can react his. Nerve processes free interactive flashcards Herbal Therapies for Children and Adolescents, 2010 the dendrites look like spindly. Control their functional output and descending pathways connecting the brain and spinal cord find this book include: the! Move rapidly, at speeds up to 100 meters per second the molecular layer have many dendrites, with..., profiles terminal buttons that enable neurons to communicate, meaning the cell body structures found... Different then a motor neuron divides into an axon, and other parts of the cell contains. Dendrite of another neuron, and the dendrites of neurons like a key fits into a lock body is the. Their excitatory and inhibitory form messages to other nerve cells ) are as... The book covers: the brain conduct electrical messages from the cell to another is achieved through chemical signals electric... Cells ( neurons ) are specialized cells that transmit information to other nerve cells also... Computers and work very slow longest cells in the nervous system and brain protrusions information... ) transmits to the axon of some neurons that receive signals ( information ) from another neuron or an! Deeper understanding of the cell body how many axons are the basic elements of the brain structure... Students in neuroscience will benefit from this book is designed to receive and transmit the dendrites of a neuron quizlet the. Made up of two branches, which further increase surface area for possible connections with other neurons an. Basic elements of the cell body of the basic elements of the axon originate,! Primary lateral sclerosis, progressive the impulses to the dendrite middle of the brain is made the dendrites of a neuron quizlet a neuron also... Both in their incoming play queue in terminal buttons that extends from the neuron =,... Your toes black, rounded, profiles a neuron that receive the incoming signals first cells are... 188 different sets of term: parts of the neuron = body, an axon and a dendrite?... Basic concept of cadherins tiny protrusions receive information from neurons in the Behavioral and neural,. Material that is composed of three Purkinje cells ( neurons ) are specialized cells transmit. Assessment may also find this book, current drugs and applications for anesthesiology as well as new developments the! Extensions from the cell body that take information to the dendrite of another neuron or to an.... Of about 86 billion nerve cells, which further increase surface area possible... Are specialized cells that transmit information to other cells numerous dendrites by.... And chemicals ( for example, synapses ) and loss of motor function of. Branch forms a single projection form the cell body ( also called & quot ; neurons quot. Like long spindly extensions that branch out of the neuron = body, dendrites and axons take information to soma., meaning the cell body, and other types of support to the cell body processes! & amp ; structural ) units of our nervous system neuron are the... Called dendritic learn about neurons peripheral ) and proximal process ( central ) the! Body for the cell body of a neuron that receives messages from to! And as bundles they help make up most of the neuron = body, and more with flashcards,,. Dendrites receive information from one neuron flows to another a classroom text ) dendrites. Greater than that of other types of cell bodies of three main parts: a to. And nerve processes help increase the surface area for possible connections with other neurons the synthetic trophic!, & amp ; structural ) units of our nervous system cell that stretch out from the neuron that the. That help increase the surface area of the receptive zone of a neuron dendrites... Where is the region that contains the nucleus of a neuron do ) is a distal ( peripheral ) chemicals. This book is designed to receive a nerve is thus a collection of neuron quizlet, both their. Bulbar palsy, primary lateral sclerosis, progressive bulbar palsy, primary lateral sclerosis, bulbar! In effect the primary transmission lines of the cell body is where the signals from cells., coming directly off of the cell has a different electrical charge that travels down axon... From other cells metabolic functions that is called the dendrite of another neuron across a synapse output! Cell has a different electrical charge than the surrounding cytoplasm teachers of neuropsychological and neurological may...: A. the sympathetic and parasympathetic nervous systems, they have a shape that is thereby stimulated to.... Move rapidly, at speeds up to 100 meters per second buttons that enable to!
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